# Trial risk translator | GLP1Nerds

Canonical: https://glp1nerds.com/tools/trial-risk-translator/

Compare absolute and relative effects using cumulative rates for the same unwanted event and follow-up period, without treating a trial result as personal risk.

# Trial risk translator

Compare absolute and relative effects using cumulative rates for the same unwanted event and follow-up period, without treating a trial result as personal risk.

## Start with your own inputs.

Your result will appear here after you complete the worksheet.

## How to read the result

The absolute difference is the control percentage minus the treatment percentage. The risk ratio divides treatment by control; relative reduction is one minus that ratio.

For unequal unwanted-event rates, 100 divided by the absolute percentage-point difference gives the number needed, rounded upward. NNTB labels an additional beneficial outcome; NNTH labels an additional harmful outcome. The comparison and follow-up period remain essential.

This worksheet does not calculate confidence intervals, account for competing risks, translate hazard ratios or predict an individual outcome. Rounded rates may produce a different number than a publication’s underlying data.

### Method and context

- [Cochrane Handbook, Chapter 15: interpreting results](https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-15)

## Keep the context

- [Who SELECT studied](https://glp1nerds.com/research/cardiovascular-outcomes-select/)

- [Read kidney outcomes with their denominator](https://glp1nerds.com/research/semaglutide-kidney-outcomes-flow/)

- [Keep direct trial comparisons specific](https://glp1nerds.com/research/semaglutide-vs-tirzepatide/)

[All tools](https://glp1nerds.com/tools/)